{"product_id":"transglutaminase-2-tgm2-rabbit-pab-a0981","title":"Transglutaminase 2 (TGM2) Rabbit pAb - A0981","description":"\u003cp\u003eTransglutaminase 2 (TGM2) Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A0981-20, A0981-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, IF\/ICC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 77kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 77kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment)\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 7052\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P21980\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: TGC; tTG; G (h) ; hTG2; TG (C) ; Transglutaminase 2 (TGM2)\u003c\/p\u003e \n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 IF\/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics Nuclear Signaling, Cancer, Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Endocrine Metabolism, Amino acid metabolism, Immunology Inflammation, Neuroscience, Calcium Signaling, Neurodegenerative Diseases.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: TGM2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189455446195,"sku":"A0981-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189455478963,"sku":"A0981-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_79b521c2-8551-4697-b85c-686115984fa6.png?v=1766427559","url":"https:\/\/afsbio.com\/products\/transglutaminase-2-tgm2-rabbit-pab-a0981","provider":"AFSBio Inc.","version":"1.0","type":"link"}