{"product_id":"trib2-monoclonal-antibody-bt-mca3781","title":"TRIB2 Monoclonal Antibody - BT-MCA3781","description":"\u003cp\u003eTRIB2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3781-50, BT-MCA3781-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C\/EBPalpha (CCAAT\/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction, Cancer, Stem cells, Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TRIB2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 8F9B9\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2a\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: TRIB2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human TRIB2 (AA: 1-200) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 38.8kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q92519\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: C5FW, TRB2, GS3955\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 28951\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238384689331,"sku":"BT-MCA3781-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238384722099,"sku":"BT-MCA3781-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8ef3ae3b-1fd6-4426-81a4-0ebb33be67d7.png?v=1769379661","url":"https:\/\/afsbio.com\/products\/trib2-monoclonal-antibody-bt-mca3781","provider":"AFSBio Inc.","version":"1.0","type":"link"}