{"product_id":"trimethyl-histone-h3-k56-rabbit-pab-a7262","title":"TriMethyl-Histone H3-K56 Rabbit pAb - A7262","description":"\u003cp\u003eTriMethyl-Histone H3-K56 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A7262-20, A7262-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Methylated Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF\/ICC, ELISA, ChIP-seq\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse, Rat, Other (Wide Range Predicted)\u003c\/p\u003e \n\n\u003cp\u003eProtein Weight: 15 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 17 kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 8290\/8350\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q16695\/P68431\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: H3t; H3.4; H3\/g; H3FT; H3C16; HIST3H3; TriMethyl-Histone H3-K56\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:2000 IF\/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements. ChIP-seq, 1:20 - 1:100\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics Nuclear Signaling, Protein phosphorylation, Signal Transduction, MAPK-Erk Signaling Pathway.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: H3-4\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45190028525747,"sku":"A7262-20","price":179.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45190028558515,"sku":"A7262-100","price":515.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_6683a65f-7ccc-46a2-8da5-fa0a6fee208f.png?v=1766440240","url":"https:\/\/afsbio.com\/products\/trimethyl-histone-h3-k56-rabbit-pab-a7262","provider":"AFSBio Inc.","version":"1.0","type":"link"}