{"product_id":"trk-aphospho-tyr496polyclonal-antibody-bs65110","title":"Trk A(Phospho-Tyr496)Polyclonal Antibody-BS65110","description":"\u003cp\u003eTrk A(Phospho-Tyr496)Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS65110-50, BS65110-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P04629\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eTrk A(Phospho-Tyr496)Polyclonal Antibody-BS65110\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF\/ICC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eBackground: neurotrophic receptor tyrosine kinase 1(NTRK1) Homo sapiens This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Phospho-Trk A (Y496) Polyclonal Antibody detects endogenous levels of Trk A protein only when phosphorylated at Y496.\u003c\/p\u003e\n\n\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using Trk A (Phospho-Tyr496) Antibody, Immunofluorescence analysis of NIH\/3T3 cells, using Trk A (Phospho-Tyr496) Antibody. The picture on the right is blocked with the phospho peptide.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: NTRK1; MTC; TRK; TRKA; High affinity nerve growth factor receptor; Neurotrophic tyrosine kinase receptor type 1; TRK1-transforming tyrosine kinase protein; Tropomyosin-related kinase A; Tyrosine kinase receptor; Tyrosine kinase receptor A;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human Trk A around the phosphorylation site of Tyr496. AA range:471-520\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylation\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42962785304755,"sku":"BS65110-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42962785337523,"sku":"BS65110-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_573d8793-0fc2-4554-b58b-af96e921ecab.jpg?v=1705318936","url":"https:\/\/afsbio.com\/products\/trk-aphospho-tyr496polyclonal-antibody-bs65110","provider":"AFSBio Inc.","version":"1.0","type":"link"}