{"product_id":"trml2-rabbit-polyclonal-antibody-es11279","title":"TRML2 Rabbit Polyclonal Antibody - ES11279","description":"\u003cp\u003eTRML2 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES11279-50, ES11279-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties (Allcock et al., 2003 [PubMed 12645956]).[supplied by OMIM, Mar 2008],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human protein. at AA range: 30-110\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: TRML2\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: TRML2 Polyclonal Antibody detects endogenous levels of protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Detected in cultured B-cells, T-cell leukemia and monocyte leukemia, Expressed constitutively on CD8 T-cells and induced on CD4 T-cells after activation,\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 35kD\u003c\/p\u003e\n\n\u003cp\u003eFunction: Function: Cell surface receptor that may play a role in the innate and adaptive immune response. Acts as a counterreceptor for CD276 and interaction with CD276 on T-cells enhances T-cell activation\u003cbr\u003e\nInduction: Induced in CD4 T-cells by concanavalin A\u003cbr\u003e\nSimilarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain\u003cbr\u003e\nSubunit: Interacts with CD276 and this interaction enhances T-cell activation\u003cbr\u003e\nTissue Specificity: Detected in cultured B cells, T cell leukemia and monocyte leukemia. Expressed constitutively on CD8 T-cells and induced on CD4 T-cells after activation\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Cell membrane, Single-pass type I membrane protein\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: TREML2 C6orf76 TLT2 UNQ6268\/PRO20473\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: Trem-like transcript 2 protein (TLT-2) (Triggering receptor expressed on myeloid cells-like protein 2)\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q2LA85\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46314410016947,"sku":"ES11279-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46314410049715,"sku":"ES11279-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies.jpg?v=1793190497","url":"https:\/\/afsbio.com\/products\/trml2-rabbit-polyclonal-antibody-es11279","provider":"AFSBio Inc.","version":"1.0","type":"link"}