{"product_id":"trmt61b-polyclonal-antibody-e-ab-62465","title":"TRMT61B Polyclonal Antibody - E-AB-62465","description":"\u003cp\u003eTRMT61B Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-62465-60, E-AB-62465-120, E-AB-62465-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TRMT61B\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: TRMT61B\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9BVS5\u003c\/p\u003e\n\n\u003cp\u003eBackground: Methyltransferase that catalyzes the formation of N(1-methyladenine at position 58 (m1A58 in various tRNAs in mitochondrion, including tRNA(Leu (deciphering codons UUA or UUG, tRNA(Lys and tRNA(Ser (deciphering codons UCA, UCU, UCG or UCC. Catalyzes the formation of 1-methyladenosine at position 947 of mitochondrial 16S ribosomal RNA and this modification is most likely important for mitoribosomal structure and function. In addition to tRNA N(1-methyltransferase activity, also acts as a mRNA N(1-methyltransferase by mediating methylation of adenosine residues at the N(1 position of MT-ND5 mRNA, leading to interfere with mitochondrial translation.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human TRMT61B\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 52kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 52kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43148642058419,"sku":"E-AB-62465-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43148642091187,"sku":"E-AB-62465-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43148642123955,"sku":"E-AB-62465-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_b62ea7a4-22b6-4a63-8646-37e8f2cda759.png?v=1710327192","url":"https:\/\/afsbio.com\/products\/trmt61b-polyclonal-antibody-e-ab-62465","provider":"AFSBio Inc.","version":"1.0","type":"link"}