{"product_id":"troponin-i-c-phospho-thr142-rabbit-pab-es7405","title":"Troponin I-C (phospho Thr142) rabbit pAb - ES7405","description":"\u003cp\u003eTroponin I-C (phospho Thr142) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES7405-50, ES7405-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: TNNI3; TNNC1; Troponin I; cardiac muscle; Cardiac troponin I\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human TNNI3 around the phosphorylation site of Thr142. AA range:111-160\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 28kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 7137\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P19429\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: cytosol, troponin complex, sarcomere,\u003c\/p\u003e \n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202341396659,"sku":"ES7405-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202341429427,"sku":"ES7405-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_98aa98d0-f68e-485f-907f-e7e711537932.png?v=1767127006","url":"https:\/\/afsbio.com\/products\/troponin-i-c-phospho-thr142-rabbit-pab-es7405","provider":"AFSBio Inc.","version":"1.0","type":"link"}