{"product_id":"troponin-i-c-polyclonal-antibody-bt-ap09224","title":"Troponin I-C Polyclonal Antibody - BT-AP09224","description":"\u003cp\u003eTroponin I-C Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP09224-20, BT-AP09224-50, BT-AP09224-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: tnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. TNNI3 encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TNNI3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Troponin I-C Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 24008\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P19429; Mouse: P48787; Rat: P23693\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: TNNI3; TNNC1; Troponin I; cardiac muscle; Cardiac troponin I\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 7137; Mouse: 21954; Rat: 29248\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239961157811,"sku":"BT-AP09224-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239961190579,"sku":"BT-AP09224-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239961223347,"sku":"BT-AP09224-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8a28bd1c-dfce-44e2-9ee3-15b8b4c04fc6.png?v=1769401498","url":"https:\/\/afsbio.com\/products\/troponin-i-c-polyclonal-antibody-bt-ap09224","provider":"AFSBio Inc.","version":"1.0","type":"link"}