{"product_id":"trxr1-polyclonal-antibody-ra35601","title":"TRXR1 Polyclonal Antibody - RA35601","description":"TRXR1 Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA35601-50, RA35601-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: thioredoxin reductase 1 (TXNRD1) Homo sapiens This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. [provided by RefSeq, Jul 2008],\n\nCondition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: WB 1:500-2000 ELISA 1:5000-20000\n\nApplications: WB; ELISA\n\nSpecies Cross-Reactivity: Human; Rat; Mouse\n\nGeneID (Human): 7296\n\nProtein MW (KDa): 71\n\nSWISS: Q16881\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120643203251,"sku":"RA35601-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120643236019,"sku":"RA35601-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f00ff644-0233-46ad-8e4b-b42b48188dad.png?v=1773368948","url":"https:\/\/afsbio.com\/products\/trxr1-polyclonal-antibody-ra35601","provider":"AFSBio Inc.","version":"1.0","type":"link"}