{"product_id":"try2-polyclonal-antibody-bt-ap15193","title":"TRY2 Polyclonal Antibody - BT-AP15193","description":"\u003cp\u003eTRY2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15193-20, BT-AP15193-50, BT-AP15193-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Metabolism; Signal transduction; Cell biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PRSS2\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF, WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: TRY2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P07478\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: TRY2; Trypsin-2; EC 3.4.21.4; Anionic trypsinogen; Serine protease 2; Trypsin II\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5645\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239398039731,"sku":"BT-AP15193-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239398072499,"sku":"BT-AP15193-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239398105267,"sku":"BT-AP15193-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_a45292b6-00cb-47eb-a54e-bfee17e7ef7a.png?v=1769393978","url":"https:\/\/afsbio.com\/products\/try2-polyclonal-antibody-bt-ap15193","provider":"AFSBio Inc.","version":"1.0","type":"link"}