{"product_id":"tsg-101-polyclonal-antibody-ra20614","title":"Tsg 101 Polyclonal Antibody - RA20614","description":"\u003cp\u003eTsg 101 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA20614-50, RA20614-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: tumor susceptibility 101 (TSG101) Homo sapiens The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and\/or progression. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: TSG101; Tumor susceptibility gene 101 protein; ESCRT-I complex subunit TSG101\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC-p; IF\/ICC; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat; Monkey\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 7251\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 44\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q99816\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120682918067,"sku":"RA20614-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120682950835,"sku":"RA20614-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_392eb8a1-f97a-43f2-a39a-3320d889121f.png?v=1773369434","url":"https:\/\/afsbio.com\/products\/tsg-101-polyclonal-antibody-ra20614","provider":"AFSBio Inc.","version":"1.0","type":"link"}