{"product_id":"tsg101-monoclonal-antibody-bt-mca2048","title":"TSG101 Monoclonal Antibody - BT-MCA2048","description":"\u003cp\u003eTSG101 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2048-50, BT-MCA2048-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and\/or progression.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TSG101\u003c\/p\u003e\n\n\u003cp\u003eApplications: FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 5H2A12\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: TSG101\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human TSG101 (AA: 167-374) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 44kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q99816\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: TSG10, VPS23\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 7251\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238380265651,"sku":"BT-MCA2048-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238380298419,"sku":"BT-MCA2048-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b1048f63-c6f2-4194-bf6d-4ca6656c6c1b.png?v=1769379549","url":"https:\/\/afsbio.com\/products\/tsg101-monoclonal-antibody-bt-mca2048","provider":"AFSBio Inc.","version":"1.0","type":"link"}