{"product_id":"tsg101-polyclonal-antibody-bs6042","title":"TSG101 Polyclonal Antibody-BS6042","description":"\u003cp\u003eTSG101 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS6042-50, BS6042-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q99816\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB\t1:500 - 1:2000  IHC\t1:50 - 1:200  IF\t1:50 - 1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: The transformation of a normal cell to one that is malignant can result from mutations in genes that encode proteins with key regulatory functions. Examples include the retinoblastoma gene product (Rb p110), p53, VHL and APC. Using a novel cloning strategy that allows the isolation of previously uncharacterized genes encoding selectable recessive phenotypes, an additional tumor suppressor gene has been identified. This gene, termed tsg 101 for tumor susceptibility gene 101, encodes a stathmin binding domain protein. When expression of this growth inhibitory gene is blocked in NIH\/3T3 cells using antisense mRNA, the cells exhibit a transformed phenotype and are tumorigenic in SL6 mice.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: TSG101 polyclonal antibody detects endogenous levels of TSG101 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 48 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of TSG101 polyclonal antibody at 1:500 dilution\u003cbr\u003e\n Lane 1: Hela whole cell lysate (40ug)\u003cbr\u003e\n Lane 2: The Brain cord tissue lysate of Mouse (40ug)\u003cbr\u003e\n Lane 3: The Brain tissue lysate of Rat (40ug), Immunofluorescence analysis of Hela cells using TSG101 antibody at dilution of 1:50., Immunohistochemistry of paraffin-embedded Human Brain using TSG101 antibody at dilution of 1:50.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Tumor susceptibility gene 101 protein; ESCRT-I complex subunit TSG101; TSG101\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to Human TSG101.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42997563654323,"sku":"BS6042-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42997563687091,"sku":"BS6042-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_cd1d4ffd-8232-4b2b-b51a-adba628657f2.jpg?v=1706270467","url":"https:\/\/afsbio.com\/products\/tsg101-polyclonal-antibody-bs6042","provider":"AFSBio Inc.","version":"1.0","type":"link"}