{"product_id":"ttf-1-phospho-ser327-rabbit-polyclonal-antibody-bt-ap05309","title":"TTF-1 (Phospho-Ser327) Rabbit Polyclonal Antibody - BT-AP05309","description":"\u003cp\u003eTTF-1 (Phospho-Ser327) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP05309-20, BT-AP05309-50, BT-AP05309-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea| choreoathetosis| congenital hypothyroidism| and neonatal respiratory distress| and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol\/alias andapos;TTF1andapos; with another gene| transcription termination factor 1| which plays a role in ribosomal gene transcription.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NKX2-1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: TTF-1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P43699; Mouse: P50220; Rat: P23441\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: TTF-1;Ser327; Homeobox protein Nkx-2.1; Homeobox protein NK-2 homolog A; Thyroid nuclear factor 1; Thyroid transcription factor 1; TTF-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 7080; Mouse: 21869\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239028646067,"sku":"BT-AP05309-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239028678835,"sku":"BT-AP05309-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239028711603,"sku":"BT-AP05309-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_28d8b6ee-9d9a-4bcb-90b3-a797d7748397.png?v=1769388121","url":"https:\/\/afsbio.com\/products\/ttf-1-phospho-ser327-rabbit-polyclonal-antibody-bt-ap05309","provider":"AFSBio Inc.","version":"1.0","type":"link"}