{"product_id":"ttr-mouse-monoclonal-antibody-9a6-bt-mca1252","title":"TTR mouse Monoclonal Antibody (9A6) - BT-MCA1252","description":"\u003cp\u003eTTR mouse Monoclonal Antibody (9A6)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-MCA1252-20, BT-MCA1252-50, BT-MCA1252-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein| it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported| most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and\/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience; Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TTR\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Transthyretin\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P02766; Mouse: P07309\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Transthyretin; ATTR; Prealbumin; TBPA\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 7276\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240051466419,"sku":"BT-MCA1252-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240051499187,"sku":"BT-MCA1252-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240051531955,"sku":"BT-MCA1252-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_93860f3a-651b-4a8e-86f2-cf974f5a8ac2.png?v=1769402714","url":"https:\/\/afsbio.com\/products\/ttr-mouse-monoclonal-antibody-9a6-bt-mca1252","provider":"AFSBio Inc.","version":"1.0","type":"link"}