{"product_id":"tubμlin-γ-f414-polyclonal-antibody-bs1483","title":"Tubμlin γ (F414) Polyclonal Antibody - BS1483","description":"\u003cp\u003eTubμlin γ (F414) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS1483-50, BS1483-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: TUB4, the gene for Saccharomyces cerevisiae γ-Tubμlin, encodes a 473 amino acid structural protein that localizes to the spindle pole body. γ Tubμlin, an essential protein for cell growth, organizes microtubμle arrays in the nucleus and cytoplasm. γ Tubμlin-depleted cells fail to form functional spindles and arrest during nuclear division. γ Tubμlin associates with spindle body components Spc97 and Spc98 to form the γ Tubμlin complex. The budding yeast γ Tubμlin complex contains one molecμle each of Spc97 and Spc98 and two molecμles of γ Tubμlin. In the SPB, Spc110 binds Spc97 and Spc98 of the γ Tubμlin complex. 2D gel analysis indicates five isoforms of γ Tubμlin. The phosphorylation of γ Tubμlin at Tyr 445 plays a regμlatory role in microtubμle formation. The incidence rate for this phosphorylation event peaks during G1.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Tubμlin gamma-1 chain, Gamma-1-tubμlin, Gamma-tubμlin complex component 1, GCP-1, TUBG1, TUBG, Tubμlin γ1, Tubμlin-γ1, Tubμlinγ1\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodification\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 380-430 of Human Tubμlin γ.\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Tubμlin γ (F414) polyclonal antibody detects endogenous levels of Tubμlin γ protein.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 51 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: P23258\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45936751607987,"sku":"BS1483-50","price":274.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45936751640755,"sku":"BS1483-100","price":457.5,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image.jpg?v=1788296056","url":"https:\/\/afsbio.com\/products\/tub%ce%bclin-%ce%b3-f414-polyclonal-antibody-bs1483","provider":"AFSBio Inc.","version":"1.0","type":"link"}