{"product_id":"tuberin-phospho-tyr1571-rabbit-pab-es7450","title":"Tuberin (phospho Tyr1571) rabbit pAb - ES7450","description":"\u003cp\u003eTuberin (phospho Tyr1571) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES7450-50, ES7450-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: TSC2; TSC4; Tuberin; Tuberous sclerosis 2 protein\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human TSC2 around the phosphorylation site of Tyr1571. AA range:1537-1586\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 170kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 7249\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P49815\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm. Membrane; Peripheral membrane protein. At steady state found in association with membranes.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202343231667,"sku":"ES7450-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202343264435,"sku":"ES7450-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_b86cd8e1-ea5a-4aff-9739-fba9bbaf10c2.png?v=1767127048","url":"https:\/\/afsbio.com\/products\/tuberin-phospho-tyr1571-rabbit-pab-es7450","provider":"AFSBio Inc.","version":"1.0","type":"link"}