{"product_id":"tuberin-polyclonal-antibody-bz17036","title":"Tuberin Polyclonal Antibody-BZ17036","description":"\u003cp\u003eTuberin Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BZ17036-50, BZ17036-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P49815\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, FC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000 IHC: 1\/50-1\/100 FC: 1\/50-1\/100\u003c\/p\u003e \n\n\u003cp\u003eBackground: Tuberin is a product of the TSC2 tumor suppressor gene and an important regulator of cell proliferation and tumor development. Mutations in either TSC2 or the related TSC1 (hamartin) gene cause tuberous sclerosis complex (TSC), an autosomal dominant disorder characterized by development of multiple, widespread non-malignant tumors. Tuberin is directly phosphorylated at Thr1462 by Akt\/PKB. Phosphorylation at Thr1462 and Tyr1571 regulates tuberin-hamartin complexes and tuberin activity.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 201 kDa; Observed MW: 201 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Tuberin in U87-MG lysates using Tuberin antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: TSC2; Tuberous sclerosis 2 homolog protein; Tuberous sclerosis 2 protein; Tuberin; TSC4\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human Tuberin\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42916164272307,"sku":"BZ17036-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42916164305075,"sku":"BZ17036-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_b685b828-398f-49ca-b561-62352fa5692d.jpg?v=1703418204","url":"https:\/\/afsbio.com\/products\/tuberin-polyclonal-antibody-bz17036","provider":"AFSBio Inc.","version":"1.0","type":"link"}