{"product_id":"txnrd1-polyclonal-antibody-e-ab-66881","title":"TXNRD1 Polyclonal Antibody - E-AB-66881","description":"TXNRD1 Polyclonal Antibody\n\nSizes: 60μL, 120μL, 200μL\n\nCatalogue Numbers: E-AB-66881-60, E-AB-66881-120, E-AB-66881-200\n\nCitations, Manuals and MSDS Available upon request.\n\nAbbreviation: TXNRD1\n\nTarget Synonym: TXNRD1; GRIM-12; TR; TR1; TRXR1; TXNR\n\nResearch Areas: Signal Transduction,Cell Biology,Metabolism\n\nConjugation: Unconjugated\n\nHost: Rabbit\n\nSpecies Reactivity: Human, Mouse, Rat\n\nApplication: IHC, IF\n\nIsotype: IgG\n\nClonality: Polyclonal\n\n \n\nUNIProt ID: Q16881\n\nBackground: This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.\n\nConcentration: 1mg\/mL\n\nImmunogen: Recombinant protein of human TXNRD1\n\nBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\n\nPurification Method: Affinity purification\n\nDilution: IHC \t1:50-1:100   IF \t1:50-1:200\n\n \n\n \n\nStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\n\nShipping: Ice bag\n\nResearch Use Only","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43135868698803,"sku":"E-AB-66881-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43135868731571,"sku":"E-AB-66881-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43135868764339,"sku":"E-AB-66881-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_8c158fbe-ce76-4dc9-8f34-4bed4ce7fb81.png?v=1709985777","url":"https:\/\/afsbio.com\/products\/txnrd1-polyclonal-antibody-e-ab-66881","provider":"AFSBio Inc.","version":"1.0","type":"link"}