{"product_id":"tyk2-phospho-tyr1054-1055-rabbit-polyclonal-antibody-ra35750","title":"Tyk2 (phospho-Tyr1054\/1055) Rabbit Polyclonal Antibody - RA35750","description":"\u003cp\u003eTyk2 (phospho-Tyr1054\/1055) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA35750-50, RA35750-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: tyrosine kinase 2 (TYK2) Homo sapiens This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB 1:1000-2000\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)\u003c\/p\u003e \n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 7297\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 134\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P29597\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45122474967219,"sku":"RA35750-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45122474999987,"sku":"RA35750-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c42d82f4-4fd2-4e9c-bc0d-1edf0ab3521c.png?v=1773342847","url":"https:\/\/afsbio.com\/products\/tyk2-phospho-tyr1054-1055-rabbit-polyclonal-antibody-ra35750","provider":"AFSBio Inc.","version":"1.0","type":"link"}