{"product_id":"u17l2-rabbit-polyclonal-antibody-es12462","title":"U17L2 Rabbit Polyclonal Antibody - ES12462","description":"\u003cp\u003eU17L2 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES12462-50, ES12462-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: DUB3 is a member of the ubiquitin processing protease (UBP) subfamily of deubiquitinating enzymes. See USP1 (MIM 603478) for background information.[supplied by OMIM, Mar 2008],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human U17L2 AA range: 321-371\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: U17L2\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: This antibody detects endogenous levels of U17L2 at Human\/Mouse\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1：500-2000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Broadly expressed,\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 58kD\u003c\/p\u003e\n\n\u003cp\u003eFunction: Catalytic Activity: Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol\u003cbr\u003e\nCaution: The RS447 megasatellite DNA is a highly polymorphic conserved tandem repetitive sequence which contains a copy of USP17. It is present with an interindividual variation in copy number and between 20 to 103 copies can be found both on chromosome 4 and chromosome 8\u003cbr\u003e\nCaution: The RS447 megasatellite DNA is a highly polymorphic conserved tandem repetitive sequence which contains a copy of USP17. It is present with an interindividual variation in copy number and between 20 to 103 copies can be found in the genome both on chromosome 4 and chromosome 8\u003cbr\u003e\nFunction: Functions in cell apoptosis. Cleaves ubiquitin fusion protein substrates\u003cbr\u003e\nFunction: Functions in cell apoptosis. Cleaves ubiquitin fusion protein substrates. May also bind hyaluronan and RNA\u003cbr\u003e\nInduction: Up-regulated by interleukin-4 and interleukin-6 (\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus Endoplasmic reticulum\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: USP17L2 DUB3\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: U17L2\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q7M764\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46314717184179,"sku":"ES12462-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46314717216947,"sku":"ES12462-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies.jpg?v=1793190497","url":"https:\/\/afsbio.com\/products\/u17l2-rabbit-polyclonal-antibody-es12462","provider":"AFSBio Inc.","version":"1.0","type":"link"}