{"product_id":"u2af1-polyclonal-antibody-bs7399","title":"U2AF1 Polyclonal Antibody-BS7399","description":"\u003cp\u003eU2AF1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS7399-50, BS7399-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q01081\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB 1:500 - 1:2000\u003cbr\u003e\nIHC 1:50 - 1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: U2 auxiliary factor (U2AF), comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2 (RNU2) small nuclear RNA auxiliary factor 1 (U2AF1,synonyms: RN, FP793, U2AF35, U2AFBP, RNU2AF1)is the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. The U2AF1 gene is localized to chromosome 21q22.3, which is the critical region for three diseases, progressive myoclonus epilepsy, autoimmune polyglandular disease type 1, and one form of bipolar affective disorder.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: U2AF1 polyclonal antibody detects endogenous levels of U2AF1 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 38 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western Blot analysis of U2AF1 polyclonal antibody\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: RNU2AF1; \u003cbr\u003e\nSplicing factor U2AF 35 kDa subunit; \u003cbr\u003e\nU2 auxiliary factor 35 kDa subunit; \u003cbr\u003e\nU2 small nuclear ribonucleoprotein auxillary factor 35 KD subunit; \u003cbr\u003e\nU2 small nuclear RNA auxiliary factor 1; \u003cbr\u003e\nU2 snRNP auxiliary factor small subunit; \u003cbr\u003e\nU2(RNU2) small nuclear RNA auxiliary factor 1; \u003cbr\u003e\nU2(RNU2) small nuclear RNA auxiliary factor binding protein; \u003cbr\u003e\nU2AF1; \u003cbr\u003e\nU2AF1_HUMAN; \u003cbr\u003e\nU2AF35; \u003cbr\u003e\nU2AFBP;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Recombinant full length Human U2AF1.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42923469832371,"sku":"BS7399-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42923469865139,"sku":"BS7399-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_f97c089d-93a0-44c7-96cb-20522fbd5d2f.jpg?v=1703850057","url":"https:\/\/afsbio.com\/products\/u2af1-polyclonal-antibody-bs7399","provider":"AFSBio Inc.","version":"1.0","type":"link"}