{"product_id":"uaca-polyclonal-antibody-e-ab-17184","title":"UACA Polyclonal Antibody - E-AB-17184","description":"\u003cp\u003eUACA Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-17184-60, E-AB-17184-120, E-AB-17184-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: UACA\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: FLJ10128; KIAA1561; MGC141967; MGC141969; Nuclear membrane binding protein; NUCLING; UACA; UACA; Uveal autoantigen with coiled coil domains and ankyrin repeats; Uveal autoantigen with coiled-coil domains and ankyrin repeats\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell biology, Immunology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9BZF9\u003c\/p\u003e\n\n\u003cp\u003eBackground: Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3\/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity).\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.8 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Fusion protein of human UACA\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:30-150, ELISA 1:2000-10000\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43130649313459,"sku":"E-AB-17184-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43130649346227,"sku":"E-AB-17184-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43130649378995,"sku":"E-AB-17184-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_9013b69e-2c6d-4c8c-9d90-25b65393cf52.png?v=1709810730","url":"https:\/\/afsbio.com\/products\/uaca-polyclonal-antibody-e-ab-17184","provider":"AFSBio Inc.","version":"1.0","type":"link"}