{"product_id":"ube4a-polyclonal-antibody-bt-ap09367","title":"UBE4A Polyclonal Antibody - BT-AP09367","description":"\u003cp\u003eUBE4A Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP09367-20, BT-AP09367-50, BT-AP09367-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: UBE4A encodes a member of the U-box ubiquitin ligase family. The ubiquitination factor E4A is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: UBE4A\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: UBE4A Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 122561\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q14139; Rat: Q6P7A2\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: UBE4A; KIAA0126; Ubiquitin conjugation factor E4 A\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 9354; Rat: 315608\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239969415347,"sku":"BT-AP09367-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239969448115,"sku":"BT-AP09367-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239969480883,"sku":"BT-AP09367-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_92ba786d-5335-4cbb-9bbb-73fb9c043823.png?v=1769401632","url":"https:\/\/afsbio.com\/products\/ube4a-polyclonal-antibody-bt-ap09367","provider":"AFSBio Inc.","version":"1.0","type":"link"}