{"product_id":"ucn3-polyclonal-antibody-e-ab-17833","title":"UCN3 Polyclonal Antibody - E-AB-17833","description":"\u003cp\u003eUCN3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-17833-60, E-AB-17833-120, E-AB-17833-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: UCN3\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: MGC119002; OTTHUMP00000018999 ; Prepro urocortin 3; SCP; SPC; Stresscopin ; Ucn III ; UCN3 ; UCN3 urocortin 3 stresscopin; UCNIII; Urocortin 3; Urocortin 3 stresscopin; Urocortin III\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q969E3\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the sauvagine\/corticotropin-releasing factor\/urotensin I family of proteins. The encoded preproprotein is proteolytically processed to generate the mature peptide hormone, which is secreted by pancreatic beta and alpha cells. This hormone is an endogenous ligand for corticotropin-releasing factor receptor 2 and may regulate insulin secretion in response to plasma glucose levels. Patients with type 2 diabetes exhibit reduced levels of the encoded protein in beta cells. In the brain, the encoded protein may be responsible for the effects of stress on appetite.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1.4 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human UCN3\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:300, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43130659766451,"sku":"E-AB-17833-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43130659799219,"sku":"E-AB-17833-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43130659831987,"sku":"E-AB-17833-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_8de65c21-8f63-47f9-8358-301baaeba24d.png?v=1709810941","url":"https:\/\/afsbio.com\/products\/ucn3-polyclonal-antibody-e-ab-17833","provider":"AFSBio Inc.","version":"1.0","type":"link"}