{"product_id":"ula1-polyclonal-antibody-bt-ap15352","title":"ULA1 Polyclonal Antibody - BT-AP15352","description":"\u003cp\u003eULA1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15352-20, BT-AP15352-50, BT-AP15352-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimerandapos;s disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S\/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cell biology; Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: NAE1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: NEDD8-activating enzyme E1 regulatory subunit\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q13564; Mouse: Q8VBW6; Rat: Q9Z1A5\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: NEDD8-activating enzyme E1 regulatory subunit;Amyloid beta precursor protein-binding protein 1, 59 kDa;APP-BP1;Amyloid protein-binding protein 1;Proto-oncogene protein 1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 8883\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239405772979,"sku":"BT-AP15352-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239405805747,"sku":"BT-AP15352-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239405838515,"sku":"BT-AP15352-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c183b4bc-b67e-4acb-9084-8c843d2f276f.png?v=1769394072","url":"https:\/\/afsbio.com\/products\/ula1-polyclonal-antibody-bt-ap15352","provider":"AFSBio Inc.","version":"1.0","type":"link"}