{"product_id":"upa-polyclonal-antibody-ra35916","title":"uPA Polyclonal Antibody - RA35916","description":"uPA Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA35916-50, RA35916-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: plasminogen activator, urokinase (PLAU) Homo sapiens This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA) . HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA) . This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016],\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/40000. Not yet tested in other applications.\n\nAlternative Names: PLAU; Urokinase-type plasminogen activator; U-plasminogen activator; uPA\n\nApplications: IHC-p; IF (paraffin section) ; ELISA\n\nSpecies Cross-Reactivity: Human; Rat; Mouse\n\nGeneID (Human): 5328\n\nSWISS: P00749\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120371851443,"sku":"RA35916-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120371884211,"sku":"RA35916-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b6876b6f-4536-4911-8664-5fd928478657.png?v=1773357905","url":"https:\/\/afsbio.com\/products\/upa-polyclonal-antibody-ra35916","provider":"AFSBio Inc.","version":"1.0","type":"link"}