{"product_id":"utp14a-rabbit-polyclonal-antibody-es3682","title":"UTP14A Rabbit Polyclonal Antibody - ES3682","description":"\u003cp\u003eUTP14A Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES3682-50, ES3682-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the uridine triphosphate 14 family. As an essential component of a large ribonucleoprotein complex bound to the U3 small nucleolar RNA, the encoded protein is involved in ribosome biogenesis and 18S rRNA synthesis. An autosomal retrotransposed copy of this X-linked gene exists on chromosome 13. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: UTP14A, SDCCAG16, U3 small nucleolar RNA-associated protein 14 homolog A, Antigen NY-CO-16, Serologically defined colon cancer antigen 16\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human UTP14A. AA range:321-370\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: UTP14A\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: UTP14A Polyclonal Antibody detects endogenous levels of UTP14A protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Ubiquitously expressed,\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 85kD\u003c\/p\u003e\n\n\u003cp\u003eFields: Ribosome biogenesis in eukaryotes\u003c\/p\u003e\n\n\u003cp\u003eFunction: Function: May be required for ribosome biogenesis\u003cbr\u003e\nMiscellaneous: The human genome also contains the UTP14C gene, an autosomal retrotransposed copy of this X-linked gene. Evolution of autosomal retrogenes from X-linked progenitors compensates for X-chromosome silencing during male meiosis\u003cbr\u003e\nPTM: Phosphorylated upon DNA damage, probably by ATM or ATR\u003cbr\u003e\nSimilarity: Belongs to the UTP14 family\u003cbr\u003e\nTissue Specificity: Ubiquitously expressed\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Nucleus, nucleolus\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: UTP14A\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: U3 small nucleolar RNA-associated protein 14 homolog A\u003c\/p\u003e\n\n\u003cp\u003eMouse Gene ID: 72554\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q640M1\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46316501336243,"sku":"ES3682-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46316501369011,"sku":"ES3682-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies_d75295e2-ffc1-4e0f-a3e7-87715c8983a9.jpg?v=1793190507","url":"https:\/\/afsbio.com\/products\/utp14a-rabbit-polyclonal-antibody-es3682","provider":"AFSBio Inc.","version":"1.0","type":"link"}