{"product_id":"utro-polyclonal-antibody-bt-ap15394","title":"UTRO Polyclonal Antibody - BT-AP15394","description":"\u003cp\u003eUTRO Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15394-20, BT-AP15394-50, BT-AP15394-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction; Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: UTRN\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Utrophin\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P46939\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Utrophin;Dystrophin-related protein 1;DRP-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 7402\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239407345843,"sku":"BT-AP15394-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239407378611,"sku":"BT-AP15394-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239407411379,"sku":"BT-AP15394-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_a7ed9418-4811-4af2-bca1-1b9daab1ad7c.png?v=1769394087","url":"https:\/\/afsbio.com\/products\/utro-polyclonal-antibody-bt-ap15394","provider":"AFSBio Inc.","version":"1.0","type":"link"}