{"product_id":"uvrag-polyclonal-antibody-bt-ap15395","title":"UVRAG Polyclonal Antibody - BT-AP15395","description":"\u003cp\u003eUVRAG Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15395-20, BT-AP15395-50, BT-AP15395-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cardiovascular; Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: UVRAG\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: UV radiation resistance-associated gene protein\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9P2Y5\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: UV radiation resistance-associated gene protein;p63\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 7405\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239407476915,"sku":"BT-AP15395-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239407509683,"sku":"BT-AP15395-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239407542451,"sku":"BT-AP15395-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_655899b4-8430-41f5-8cfd-79f88bac225e.png?v=1769394090","url":"https:\/\/afsbio.com\/products\/uvrag-polyclonal-antibody-bt-ap15395","provider":"AFSBio Inc.","version":"1.0","type":"link"}