{"product_id":"v-atpase-d-rabbit-pab-es6522","title":"V-ATPase D rabbit pAb - ES6522","description":"\u003cp\u003eV-ATPase D rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES6522-50, ES6522-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c\", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein. [provided by RefSeq, Jul 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: ATP6V1D; ATP6M; VATD; V-type proton ATPase subunit D; V-ATPase subunit D; V-ATPase 28 kDa accessory protein; Vacuolar proton pump subunit D\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/40000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat; Swine\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from V-ATPase D . at AA range: 70-150\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 28kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 51382\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q9Y5K8\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium. Localizes to centrosome and the base of the cilium.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202301943987,"sku":"ES6522-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202301976755,"sku":"ES6522-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_7dae03db-1bad-4beb-a90f-709498d96fbf.png?v=1767126108","url":"https:\/\/afsbio.com\/products\/v-atpase-d-rabbit-pab-es6522","provider":"AFSBio Inc.","version":"1.0","type":"link"}