{"product_id":"v-atpase-h-polyclonal-antibody-bt-ap09484","title":"V-ATPase H Polyclonal Antibody - BT-AP09484","description":"\u003cp\u003eV-ATPase H Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP09484-20, BT-AP09484-50, BT-AP09484-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: ATP6V1H encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. The V-type proton ATPase subunit H is the regulatory H subunit of the V1 domain of V-ATPase, which is required for catalysis of ATP but not the assembly of V-ATPase. Decreased expression of this gene may play a role in the development of type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ATP6V1H\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: V-ATPase H Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 55883\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9UI12; Mouse: Q8BVE3\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ATP6V1H; CGI-11; V-type proton ATPase subunit H; V-ATPase subunit H; Nef-binding protein 1; NBP1; Protein VMA13 homolog; V-ATPase 50\/57 kDa subunits; Vacuolar proton pump subunit H; Vacuolar proton pu\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 51606; Mouse: 108664\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239977738419,"sku":"BT-AP09484-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239977771187,"sku":"BT-AP09484-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239977803955,"sku":"BT-AP09484-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_0c0b2444-086c-4f6c-8098-e0385d49ac1e.png?v=1769401726","url":"https:\/\/afsbio.com\/products\/v-atpase-h-polyclonal-antibody-bt-ap09484","provider":"AFSBio Inc.","version":"1.0","type":"link"}