{"product_id":"vash1-polyclonal-antibody-e-ab-92705","title":"VASH1 Polyclonal Antibody - E-AB-92705","description":"\u003cp\u003eVASH1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-92705-60, E-AB-92705-120, E-AB-92705-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: VASH1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: VASH1; KIAA1036\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q7L8A9\u003c\/p\u003e\n\n\u003cp\u003eBackground: Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function. Critical for spindle function and accurate chromosome segregation during mitosis since microtuble detyronisation regulates mitotic spindle length and postioning. Acts as an angiogenesis inhibitor: inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human VASH1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 21kDa\/40kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 41kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146651697331,"sku":"E-AB-92705-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146651730099,"sku":"E-AB-92705-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146651762867,"sku":"E-AB-92705-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_b7418ae4-4ca7-4ff4-97f3-cc31d7ebe059.png?v=1710299390","url":"https:\/\/afsbio.com\/products\/vash1-polyclonal-antibody-e-ab-92705","provider":"AFSBio Inc.","version":"1.0","type":"link"}