{"product_id":"vata-polyclonal-antibody-bt-ap15423","title":"VATA Polyclonal Antibody - BT-AP15423","description":"\u003cp\u003eVATA Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15423-20, BT-AP15423-50, BT-AP15423-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, candapos;, c\", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain A subunit isoforms and is found in all\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction; Metabolism; Tags and cell markers\u003c\/p\u003e \n\n\u003cp\u003eTarget Protein: ATP6V1A\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: V-type proton ATPase catalytic subunit A\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P38606; Mouse: P50516\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: V-type proton ATPase catalytic subunit A;V-ATPase subunit A;EC 3.6.3.14;V-ATPase 69 kDa subunit;Vacuolar ATPase isoform VA68;Vacuolar proton pump subunit alpha\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 523\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239408525491,"sku":"BT-AP15423-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239408558259,"sku":"BT-AP15423-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239408591027,"sku":"BT-AP15423-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_dd571bd3-1a49-4d2e-929b-5cb078dd51ff.png?v=1769394101","url":"https:\/\/afsbio.com\/products\/vata-polyclonal-antibody-bt-ap15423","provider":"AFSBio Inc.","version":"1.0","type":"link"}