{"product_id":"vav3-rabbit-pab-es4476","title":"Vav3 rabbit pAb - ES4476","description":"\u003cp\u003eVav3 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES4476-50, ES4476-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: VAV3; Guanine nucleotide exchange factor VAV3; VAV-3\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human VAV3. AA range:139-188\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 98kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 10451\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q9UKW4\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: intracellular, cytosol, plasma membrane, extracellular exosome,\u003c\/p\u003e \n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202198462643,"sku":"ES4476-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202198495411,"sku":"ES4476-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_d68cc3bb-ed8e-4f31-9507-7bbecbcb057c.png?v=1767124052","url":"https:\/\/afsbio.com\/products\/vav3-rabbit-pab-es4476","provider":"AFSBio Inc.","version":"1.0","type":"link"}