{"product_id":"vcam1-polyclonal-antibody-e-ab-70284","title":"VCAM1 Polyclonal Antibody - E-AB-70284","description":"\u003cp\u003eVCAM1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-70284-60, E-AB-70284-120, E-AB-70284-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: VCAM1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: CD106; CD106 Antigen; INCAM 100; INCAM-100; L1CAM; MGC99561; V-CAM 1; Vascular Cell Adhesion Molecule 1; Vascular cell adhesion protein 1; VCAM 1; VCAM-1; VCAM1; VCAM1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cardiovascular, Neuroscience, Signal Transduction, Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P29533\u003c\/p\u003e\n\n\u003cp\u003eBackground: Vascular cell adhesion molecule 1 (VCAM1), also known as CD106, is a transmembrane glycoprotein belonging to the immunoglobulin gene superfamily. VCAM1 is expressed by cytokine-activated endothelium, interacts with integrin VLA4 (α4β1) present on the surface of leukocytes, and mediates both adhesion and signal transduction. It is also expressed either constitutively or inducibly in a variety of other cell types, including vascular smooth muscle cells, differentiating skeletal muscle cells, renal and neural epithelial cells, macrophages (Kupffer cells), dendritic cells, and bone marrow stromal cells .\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.63 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein corresponding to Mouse VCAM-1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 100-110kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 100-110kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146517446835,"sku":"E-AB-70284-60","price":224.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146517479603,"sku":"E-AB-70284-120","price":364.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146517512371,"sku":"E-AB-70284-200","price":574.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_46398b36-8112-4fd1-8b20-c348d3162fc5.png?v=1710296741","url":"https:\/\/afsbio.com\/products\/vcam1-polyclonal-antibody-e-ab-70284","provider":"AFSBio Inc.","version":"1.0","type":"link"}