{"product_id":"vdac1-polyclonal-antibody-bz16538","title":"VDAC1 Polyclonal Antibody-BZ16538","description":"\u003cp\u003eVDAC1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BZ16538-50, BZ16538-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P21796\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IHC: 1\/50-1\/100\u003c\/p\u003e  \n\n\u003cp\u003eBackground: Voltage-dependent anion channel (VDAC), ubiquitously expressed and located in the outer mitochondrial membrane, is generally thought to be the primary means by which metabolites diffuse in and out of the mitochondria. In addition, this channel plays a role in apoptotic signaling. The change in mitochondrial permeability characteristic of apoptosis is mediated by Bcl-2 family proteins, which bind to VDAC, altering the channel kinetics.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 31 kDa; Observed MW: 31 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Calreticulin in HepG2 lysates; Jurkat lysates using VDAC1 antibody., Immunohistochemistry analysis of paraffin-embedded Human liver using VDAC1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Western blot analysis of VDAC1 in C2C12, THP-1, 3T3, Jurakt and Hela lysates using VDAC1 antibody\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: VDAC1; PORIN; PORIN-31-HL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthesized peptide derived from human VDAC1\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42993836556467,"sku":"BZ16538-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42993836589235,"sku":"BZ16538-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_f6e8faca-9b00-49f8-aef9-bc9fe5c6f0da.jpg?v=1706184098","url":"https:\/\/afsbio.com\/products\/vdac1-polyclonal-antibody-bz16538","provider":"AFSBio Inc.","version":"1.0","type":"link"}