{"product_id":"ve-cadherin-monoclonal-antibody-e-ab-22244","title":"VE-Cadherin Monoclonal Antibody - E-AB-22244","description":"\u003cp\u003eVE-Cadherin Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-22244-60, E-AB-22244-120, E-AB-22244-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: VE-Cadherin\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: 7B 4; 7B4; 7B4 antigen; CADH5; Cadherin 5; Cadherin 5 type 2; Cadherin 5; type 2 (vascular endothelium); Cadherin 5; type 2; VE cadherin (vascular epithelium); cadherin; vascular endothelial; cadherin; vascular endothelial; 1; Cadherin-5; Cadherin5; CD 144; CD144; CD144 antigen; CDH 5; CDH5; CDH5 protein; Endothelial specific cadherin; FLJ17376; OTTHUMP00000174777; Vascular endothelial cadherin; Vascular epithelium cadherin; VE Cad; VE-cadherin; VEC\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cardiovascular, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC-p\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone No.: Clone:8E5\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P33151\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic Peptide of VE-Cadherin\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Protein A purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:100-200\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43135928991923,"sku":"E-AB-22244-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43135929024691,"sku":"E-AB-22244-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43135929057459,"sku":"E-AB-22244-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_ac5a06b0-fdf4-4e2a-9443-443a0c847b27.png?v=1709986646","url":"https:\/\/afsbio.com\/products\/ve-cadherin-monoclonal-antibody-e-ab-22244","provider":"AFSBio Inc.","version":"1.0","type":"link"}