{"product_id":"ve-cadherin-polyclonal-antibody-bt-ap15453","title":"VE-Cadherin Polyclonal Antibody - BT-AP15453","description":"\u003cp\u003eVE-Cadherin Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15453-20, BT-AP15453-50, BT-AP15453-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Cardiovascular; Signal transduction; Developmental biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CDH5\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Cadherin-5\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P33151; Mouse: P55284\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Cadherin-5;7B4 antigen;Vascular endothelial cadherin;VE-cadherin;CD antigen CD144; Cadherin-5; 7B4 antigen; Vascular endothelial cadherin; VE-cadherin; CD antigen CD144\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1003; Mouse: 12562\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239409868979,"sku":"BT-AP15453-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239409901747,"sku":"BT-AP15453-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239409934515,"sku":"BT-AP15453-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_58f70786-b3c9-408e-b4be-d413d5fe2b75.png?v=1769394117","url":"https:\/\/afsbio.com\/products\/ve-cadherin-polyclonal-antibody-bt-ap15453","provider":"AFSBio Inc.","version":"1.0","type":"link"}