{"product_id":"vegf-rabbit-polyclonal-antibody-bt-ap15454","title":"VEGF Rabbit Polyclonal Antibody - BT-AP15454","description":"\u003cp\u003eVEGF Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15454-20, BT-AP15454-50, BT-AP15454-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of the PDGF\/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been described. There is also evidence for alternative translation initiation fro\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction; Cancer; Cardiovascular; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: VEGFA\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: VEGFA\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P15692; Mouse: Q00731; Rat: P16612\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: VEGFA; VEGFA\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 7422\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239410000051,"sku":"BT-AP15454-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239410032819,"sku":"BT-AP15454-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239410065587,"sku":"BT-AP15454-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_1ef19d97-436b-4607-b994-9bd946fa6f0c.png?v=1769394118","url":"https:\/\/afsbio.com\/products\/vegf-rabbit-polyclonal-antibody-bt-ap15454","provider":"AFSBio Inc.","version":"1.0","type":"link"}