{"product_id":"vegf-receptor-2-rabbit-pab-a5609","title":"VEGF Receptor 2 Rabbit pAb - A5609","description":"\u003cp\u003eVEGF Receptor 2 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A5609-20, A5609-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 152kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 210kDa\/230kDa\/230kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3791\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P35968\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: FLK1; CD309; VEGFR; VEGFR2; VEGF Receptor 2\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Protein phosphorylation, Cancer, Invasion and Metastasis, Signal Transduction, Kinase, Tyrosine kinases, Cell Biology Developmental Biology, Growth factors, Endocrine Metabolism, Immunology Inflammation, CDs, Stem Cells, Hematopoietic Progenitors, Cardiovascular, Angiogenesis, Hypoxia.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: KDR\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189950505139,"sku":"A5609-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189950537907,"sku":"A5609-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_bc27accf-c226-4e5a-8277-364887ecc7a4.png?v=1766438694","url":"https:\/\/afsbio.com\/products\/vegf-receptor-2-rabbit-pab-a5609","provider":"AFSBio Inc.","version":"1.0","type":"link"}