{"product_id":"vgll1-polyclonal-antibody-e-ab-53198","title":"VGLL1 Polyclonal Antibody - E-AB-53198","description":"\u003cp\u003eVGLL1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-53198-60, E-AB-53198-120, E-AB-53198-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: VGLL1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Protein TONDU; TDU; TONDU; Transcription cofactor vestigial like protein 1; Transcription cofactor vestigial-like protein 1; Vestigial like 1; vestigial like 1 homolog (Drosophila); Vgl-1; VGL1; Vgll1; VGLL1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q99990\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene binds proteins of the TEA domain family of transcription factors (TEFs) through the Vg (vestigial) homology region found in its N-terminus. It may thus function as a specific coactivator for the mammalian TEFs. TDU interacted directly with the TEA domain family member, TEF1, and deletion of the Vg homology region abolished the interaction. The TDU-TEF1 dimer activated a reporter plasmid, and expression of TDU in Drosophila rescued loss of Vg function. The interaction was stronger in cardiac myocytes, suggesting a myocyte-specific factor may participate in the interaction. Vgll1 was weakly active in driving expression of a reporter gene from the mouse skeletal muscle alpha-actin promoter, and Vgll1 could partially reverse the inhibitory effect of TEF1 in this assay.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 2 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human VGLL1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:2000-1:10000 ELISA 1:2000-1:20000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 29 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43143989821619,"sku":"E-AB-53198-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43143989854387,"sku":"E-AB-53198-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43143989887155,"sku":"E-AB-53198-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_c5e732ff-b938-42a2-b88e-263dc0e8e8f9.png?v=1710244839","url":"https:\/\/afsbio.com\/products\/vgll1-polyclonal-antibody-e-ab-53198","provider":"AFSBio Inc.","version":"1.0","type":"link"}