{"product_id":"vinculin-polyclonal-antibody-bt-ap09531","title":"Vinculin Polyclonal Antibody - BT-AP09531","description":"\u003cp\u003eVinculin Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP09531-20, BT-AP09531-50, BT-AP09531-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for VCL, but the biological validity of some variants has not been determined.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: VCL\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Vinculin Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 123799\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P18206; Mouse: Q64727; Rat: P85972\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: VCL; Vinculin; Metavinculin\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 7414; Mouse: 22330; Rat: 305679\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239983734963,"sku":"BT-AP09531-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239983767731,"sku":"BT-AP09531-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239983800499,"sku":"BT-AP09531-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_7c0e71f6-fee2-4ec8-b392-bad73246f559.png?v=1769401768","url":"https:\/\/afsbio.com\/products\/vinculin-polyclonal-antibody-bt-ap09531","provider":"AFSBio Inc.","version":"1.0","type":"link"}