{"product_id":"visfatin-monoclonal-antibody-bt-mca3808","title":"Visfatin Monoclonal Antibody - BT-MCA3808","description":"\u003cp\u003eVisfatin Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3808-50, BT-MCA3808-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Visfatin, a newly identified adipocytokine ,which is predominantly secreted from visceral adipose tissue both in humans and mice . Visfatin corresponds to a protein identified previously as pre-B cell colony-enhancing factor (PBEF). Visfatin exerted insulin-mimetic effects in cultured cells, various insulin-sensitive tissues such as liver, muscle, and fat ,and lowered plasma glucose levels in mice. Mice heterozygous for a targeted mutation in the visfatin gene had modestly higher levels of plasma glucose relative to wild-type littermates. visfatin binds to and activates the insulin receptor. Which may lead to new insights into glucose homeostasis and\/or new therapies for metabolic disorders such as diabetes.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: Visfatin\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 4E11C9\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Visfatin\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of Visfatin expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P43490\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PBEF, MGC117256\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 10135\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238369681587,"sku":"BT-MCA3808-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238369714355,"sku":"BT-MCA3808-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_0b469354-b5e6-4cf9-9864-43317705f6e5.png?v=1769379307","url":"https:\/\/afsbio.com\/products\/visfatin-monoclonal-antibody-bt-mca3808","provider":"AFSBio Inc.","version":"1.0","type":"link"}