{"product_id":"vma21-polyclonal-antibody-e-ab-53204","title":"VMA21 Polyclonal Antibody - E-AB-53204","description":"\u003cp\u003eVMA21 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-53204-60, E-AB-53204-120, E-AB-53204-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: VMA21\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: VMA21; Vacuolar ATPase Assembly Factor; Myopathy With Excessive Autophagy Protein; MEAX; XMEA; Vacuolar ATPase Assembly Integral Membrane Protein VMA21; VMA21 Vacuolar H+-ATPase Homolog (S. Cerevisiae); Myopathy With Excessive Autophagy; VMA21 Vacuolar H+-ATPase Homolo.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q3ZAQ7\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a chaperone for assembly of lysosomal vacuolar ATPase. Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum. Associates with the V0 complex of the vacuolar ATPase (V-ATPase). MEAX is a childhood-onset disease characterized by progressive vacuolation and atrophy of skeletal muscle. It is inherited in recessive fashion, affecting boys and sparing carrier females. Onset is in childhood, and patients exhibit weakness of the proximal muscles of the lower extremities, progressing slowly to involve other skeletal muscle groups over time.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 2.6 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human VMA21\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:150-1:500, IF 1: 50-1:200, ELISA 1:5000-1:240000\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43133576315059,"sku":"E-AB-53204-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43133576347827,"sku":"E-AB-53204-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43133576380595,"sku":"E-AB-53204-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_14c364de-9755-496e-97c5-9bb108790af4.png?v=1709900333","url":"https:\/\/afsbio.com\/products\/vma21-polyclonal-antibody-e-ab-53204","provider":"AFSBio Inc.","version":"1.0","type":"link"}