{"product_id":"vps34-phospho-ser249-polyclonal-antibody-ap4010","title":"VPS34 (phospho-Ser249) Polyclonal Antibody - AP4010","description":"\u003cp\u003eVPS34 (phospho-Ser249) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: AP4010-50, AP4010-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: μlK1 andμlK2 (for UNC-51-like kinase) encode similar amino-terminal serine\/threonine kinase domains, a proline\/serine-rich (PS) domain, and a species conserved carboxyl-terminal domain. Both share homology with the UNC-51 kinase from Caenorhabditis elegans and the APG1 kinase in yeast, which are involved in axonal extension and growth, and autophagy, respectively.μlK1 andμlK2 are thought to auto-phosphorylate the PS domain in vitro, and the significant homology among vertebrates suggest thatμlK1 andμlK2 are involved in the regμlation of fundamental biological processes.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Serine\/threonine-protein kinaseμlK1, Autophagy-related protein 1 homolog, ATG1, Unc-51-like kinase 1,μlK1, KIAA0722\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylated\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 700-800 of HumanμlK1.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: μlK1 (S757) polyclonal antibody detects endogenous levels ofμlK1 protein.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 110 kDa\u003c\/p\u003e\n\n\u003cp\u003ePathway: Phosphoinosotode Signaling,\u003c\/p\u003e \n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: Q8NEB9\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45946183286963,"sku":"AP4010-50","price":289.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45946183319731,"sku":"AP4010-100","price":492.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_6ca33534-2486-4e91-ac84-9e0d75778258.jpg?v=1788363539","url":"https:\/\/afsbio.com\/products\/vps34-phospho-ser249-polyclonal-antibody-ap4010","provider":"AFSBio Inc.","version":"1.0","type":"link"}