{"product_id":"wdr35-polyclonal-antibody-e-ab-90498","title":"WDR35 Polyclonal Antibody - E-AB-90498","description":"\u003cp\u003eWDR35 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-90498-60, E-AB-90498-120, E-AB-90498-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: WDR35\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: WDR35; CED2; IFT121; IFTA1; SRTD7\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9P2L0\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Two patients with Sensenbrenner syndrome \/ cranioectodermal dysplasia (CED) were identified with mutations in this gene, consistent with a possible ciliary function.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human WDR35\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:1000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 132kDa\/133kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 133kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43148726730931,"sku":"E-AB-90498-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43148726763699,"sku":"E-AB-90498-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43148726796467,"sku":"E-AB-90498-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_3edf0bb2-c740-4449-bad4-82f68c77546c.png?v=1710328843","url":"https:\/\/afsbio.com\/products\/wdr35-polyclonal-antibody-e-ab-90498","provider":"AFSBio Inc.","version":"1.0","type":"link"}