{"product_id":"wfs1-polyclonal-antibody-bt-ap15535","title":"WFS1 Polyclonal Antibody - BT-AP15535","description":"\u003cp\u003eWFS1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15535-20, BT-AP15535-50, BT-AP15535-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction; Neuroscience; Metabolism; Cancer\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: WFS1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Wolframin\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O76024; Mouse: P56695\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Wolframin\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 7466\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239417471155,"sku":"BT-AP15535-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239417503923,"sku":"BT-AP15535-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239417536691,"sku":"BT-AP15535-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_5edd7a81-3e3d-48c6-ae85-90868b75e4e5.png?v=1769394161","url":"https:\/\/afsbio.com\/products\/wfs1-polyclonal-antibody-bt-ap15535","provider":"AFSBio Inc.","version":"1.0","type":"link"}