{"product_id":"wnk4-polyclonal-antibody-bt-ap15547","title":"WNK4 Polyclonal Antibody - BT-AP15547","description":"\u003cp\u003eWNK4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15547-20, BT-AP15547-50, BT-AP15547-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: WNK4\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Serine\/threonine-protein kinase WNK4\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q96J92; Mouse: Q80UE6; Rat: Q7TPK6\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Serine\/threonine-protein kinase WNK4;EC 2.7.11.1;Protein kinase lysine-deficient 4;Protein kinase with no lysine 4\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 65266\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239418159283,"sku":"BT-AP15547-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239418192051,"sku":"BT-AP15547-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239418224819,"sku":"BT-AP15547-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_0e5fcace-92d1-4cda-bd11-29db1d41eeeb.png?v=1769394171","url":"https:\/\/afsbio.com\/products\/wnk4-polyclonal-antibody-bt-ap15547","provider":"AFSBio Inc.","version":"1.0","type":"link"}