{"product_id":"wnt11-polyclonal-antibody-bs65434","title":"Wnt11 Polyclonal Antibody-BS65434","description":"\u003cp\u003eWnt11 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS65434-50, BS65434-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: O96014\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eWnt11 Polyclonal Antibody-BS65434\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB,\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB=1:500-2000\u003c\/p\u003e\n\n\u003cp\u003eBackground: The Wnt genes belong to a family of protooncogenes with at least 13 known members that are expressed in species ranging from Drosophila to man. The name Wnt denotes the relationship of this family to the Drosophila segment polarity gene ”wingless” and to its vertebrate ortholog, Int-1, a mouse proto-oncogene. Transcription of Wnt family genes appears to be developmentally regulated in a precise temporal and spatial manner. The Wnt genes encode cysteine-rich putative glycoproteins which have features typical of secreted growth factors. Wnt-11 is expressed in the tips of ureteric buds and in the perichondrium, a stem cell-like layer that surrounds the future bones and directs their growth and regeneration. Wnt-11 activity is required for cells to undergo correct convergent extension movements during gastrulation. Human Wnt-11 is also expressed in the lung mesenchyme, the urorectal septum, the urogenital folds, the labioscrotal swellings, and the cortex of the adrenal gland. Unlike other Wnt family members, Wnt-11 is not expressed in the neuroepithelium of the central nervous system. Wnt-11, along with Wnt-8c, is ex-pressed in the posterior region of the chick embryo in the caudal paraxial mesoderm that underlies the prospective caudal neural plate. The gene which encodes Wnt-11 maps to human chromosome 11q13.5.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: affinity purified by Protein A\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Wnt11 Polyclonal Antibody detects endogenous levels of Wnt11 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 35 kD\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Primary: Anti- Wnt11 at 1\/1000 dilution, Primary: Anti- Wnt11 at 1\/1000 dilution\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: HWNT11; Protein Wnt-11; Wingless-related MMt V integration site 11; Wingless-type MMt V integration site family, member 1; Wingless-type MMt V integration site family, member 11; Wingless-type MMt V integration site family, member 11B; wnt-11; wnt11b.WNT11_HUMAN\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH conjugated synthetic peptide derived from human Wnt11:151-250\/354\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42962736349363,"sku":"BS65434-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42962736382131,"sku":"BS65434-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_274da3b3-a895-45b2-b1c5-976d8b10687d.jpg?v=1705318647","url":"https:\/\/afsbio.com\/products\/wnt11-polyclonal-antibody-bs65434","provider":"AFSBio Inc.","version":"1.0","type":"link"}